
What is Avmacol® Extra Strength?
Avmacol® Extra Strength is a patented, sulforaphane-producing supplement that works in combination with Maitake mushroom extract (containing beta-glucans) to support your body's natural detoxification process better than sulforaphane alone.1Avmacol® Extra Strength provides glucoraphanin, also known as sulforaphane glucosinolate, and active myrosinase enzyme, which are the essential ingredients needed for sulforaphane production. Without active myrosinase enzyme, one may not be able to reap sulforaphane’s many health-promoting benefits.
What are the Ingredients?
Avmacol® Extra Strength contains the essential ingredients necessary for sulforaphane production in the body, broccoli seed extract (Glucoraphanin) and Myrosimax® (Active Myrosinase Enzyme). Avmacol® Extra Strength also contains Maitake mushroom extract for added immune and detoxification support.
How Maitake Mushroom Extract Works in Combination with Sulforaphane
How Maitake Mushroom Extract Works in
Combination with Sulforaphane
The Maitake mushroom extract (containing beta-glucans) works in combination with sulforaphane to
support your body’s natural detoxification process better than sulforaphane alone.1In addition, the
Maitake mushroom extract found in Avmacol® Extra Strength provides the added bonus of immune
support by promoting neutrophil function and natural killer cell activity.
What are the Benefits of Sulforaphane?
Sulforaphane offers numerous health-promoting benefits, which are likely due to its positive effect on multiple cellular pathways:
Why Can't I Just Eat Broccoli?
Since sulforaphane is associated with cruciferous vegetables, namely broccoli and broccoli sprouts, many people think they can get the benefits of sulforaphane just by eating their vegetables. Unfortunately, it isn’t that simple, as sulforaphane itself is not found in broccoli. Rather it is the essential ingredients, glucoraphanin and myrosinase, that are present. Unfortunately, there may not be enough of either compound in the plant to allow for adequate sulforaphane production. This can be due to seed quality, soil composition, the age of the plant, and many other factors.
Additionally, any myrosinase enzyme that is present in the plant can be destroyed during the cooking process. So while glucoraphanin and the myrosinase enzyme can be found in the vegetables you eat, the ones you buy from the market are not necessarily reliable sources of either compound.
The Science Behind Avmacol® Extra Strength
The Science Behind Avmacol®
Extra Strength
The combination of sulforaphane and Maitake extract supports the movement (or translocation) from the cytoplasm to the nucleus of NRF2 and increases the levels of certain Phase 2 enzymes. Below are images of a technique called immunofluorescence which illustrate how much protein is being produced in the cell and the location of that protein.
he combination of sulforaphane and Maitake extract supports the movement (or
translocation) from the cytoplasm to the nucleus of NRF2 and increases the levels of
certain Phase 2 enzymes. Below are images of a technique called
immunofluorescence which illustrate how much protein is being produced in the
cell and the location of that protein.
Translocation of NRF2 into the Nucleus Following Exposure to Sulforaphane and Maitake
Mushroom Extract
In control cells (left panel), the green staining indicates that NRF2 remains largely in the cytoplasm (arrows) without much protein located in the nucleus, which is counter-stained in blue. When cells are exposed to sulforaphane and Maitake (right panel), NRF2 moves to the nucleus (arrows) where it can bind to DNA to turn on expression of certain Phase 2 enzymes.
In control cells (left panel), the green staining indicates that NRF2 remains largely in the cytoplasm
(arrows) without much protein located in the nucleus, which is counter-stained in blue. When cells are
exposed to sulforaphane and Maitake (right panel), NRF2 moves to the nucleus (arrows) where it can
bind to DNA to turn on expression of certain Phase 2 enzymes.
Sulforaphane and Maitake Extract Boosts Select Phase 2 Enzyme Production Including NQO1 and HO-1
Sulforaphane and Maitake Extract Boosts Select Phase 2
Enzyme Production Including NQO1 and HO-1
NQO1 Protein Expression in THLE2 Liver Cells
In control cells (left panel) NQO1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of NQO1 staining, representing the amount of protein, is increased.
In control cells (left panel) NQO1 protein expression is indicated by the green staining. When cells are
exposed to sulforaphane and Maitake (right panel), the level of NQO1 staining, representing the amount
of protein, is increased.
HO-1 Protein Expression in THLE2 Liver Cells
In control cells (left panel) HO-1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of HO-1 staining, representing the amount of protein, is increased.
In control cells (left panel) HO-1 protein expression is indicated by the green staining. When cells are exposed to sulforaphane and Maitake (right panel), the level of HO-1 staining, representing the amount of protein, is increased.
FAQS
What is AVMACOL® Extra Strength and what does it do?
What is AVMACOL® Extra Strength and what does it do?
It is a topical, drug-free treatment formulated to promote hair regrowth and reduce thinning for people with androgenetic alopecia (male and female pattern hair loss).
How does AVMACOL® work?
How does AVMACOL® work?
Its patented key ingredient, Synastol® FC, helps rejuvenate shrunken hair follicles, encouraging them to re-enter the growth phase (anagen) for thicker, stronger hair.
How do I apply it?
How do I apply it?
Apply 1 mL directly to the dry scalp in the affected areas once daily, preferably at the same time each day. Massage gently until absorbed. Do not wash your hair for at least 4 hours after application
How long until I see results?
How long until I see results?
Results can vary. Some users may see initial results in 3-4 months, but significant regrowth typically requires 6-12 months of consistent, daily use.
Is AVMACOL® proven by clinical studies?
Is AVMACOL® proven by clinical studies?
Yes, the key patented ingredient, Synastol® FC, has been clinically studied and shown to be effective in promoting hair regrowth.
Can women use this product?
Can women use this product?
Absolutely. AVMACOL® Extra Strength is formulated for both men and women experiencing pattern hair loss.
What are the side effects?
What are the side effects?
AVMACOL® is generally well-tolerated. Some users may experience mild, temporary scalp irritation, itching, or redness. It is drug-free and does not carry the systemic side effects associated with some oral medications.
Where should I store the bottle?
Where should I store the bottle?
Store it at room temperature, away from direct sunlight and heat. The glass bottle and dropper help protect the formula.
Is there a money-back guarantee?
Is there a money-back guarantee?
Please check the official website for their current return policy and any satisfaction guarantee details.